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Building a synthetic centrosome

Updated: Jan 16, 2020

by Jeff Woodruff

The centrosome is a structure in cells which is built every time the cell prepares to divide. In this video abstract, Jeff Woodruff explains how to build a centrosome in a test tube from purified proteins. He found that the centrosome acts like a sponge, which selectively soaks up the proteins needed to build microtubules.

Read more in the full paper, published in the journal Cell.

Related resources

• Watch a Science Sketch on the regulation of centrosome assembly by Jeff and Oliver Wüseke.

• Watch Jeff's first Science Sketch explaining his approach to studying the centrosome.

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